hdac3 ncor2 Search Results


hdac3/ncor2, active  (Sino Biological)
N/A
Recombinant human HDAC3 (full length)/NCOR2 (237-489) complex was expressed by baculovirus in Sf9 insect cells using a C-terminal GST-tag for HDAC3 and N-terminal GST-tag for NCOR2.
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hdac3 bps bioscience  (BPS Bioscience)
94
BPS Bioscience hdac3 bps bioscience
Hdac3 Bps Bioscience, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hdac3+ncor2/HDAC3%2FNcoR2%2C+His-Tag%2C+GST-Tag+Recombinant/pm38747979-277-23-24
Average 94 stars, based on 1 article reviews
hdac3 bps bioscience - by Bioz Stars, 2026-10
94/100 stars
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i e hdac3 ncor2  (SignalChem)
90
SignalChem i e hdac3 ncor2
The reported <t>HDAC3-selective</t> inhibitors for the treatment of a range of diseases.
I E Hdac3 Ncor2, supplied by SignalChem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hdac3+ncor2/HDAC3%2FNCOR2%2C+Active/pmc05978667-140-7-20
Average 90 stars, based on 1 article reviews
i e hdac3 ncor2 - by Bioz Stars, 2026-10
90/100 stars
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hdac3/ ncor2  (Verlag GmbH)
90
Verlag GmbH hdac3/ ncor2
The reported <t>HDAC3-selective</t> inhibitors for the treatment of a range of diseases.
Hdac3/ Ncor2, supplied by Verlag GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hdac3+ncor2/hdac3++ncor2/10__1002_slash_anie__200703198-102-20-6
Average 90 stars, based on 1 article reviews
hdac3/ ncor2 - by Bioz Stars, 2026-10
90/100 stars
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hdac3 ncor2  (Cayman Chemical)
N/A
Histone deacetylases HDACs catalyze the deacetylation of core histones resulting in tightening of nucleosomal integrity restriction of the access of transcription factors and suppression of transcription HDACs also play an important role in mediating nuclear
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Image Search Results


The reported HDAC3-selective inhibitors for the treatment of a range of diseases.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: The reported HDAC3-selective inhibitors for the treatment of a range of diseases.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques:

The workflow for the discovery of novel HDAC3 inhibitors. The number refers to the amount of chemical entities that entered the next component of the workflow.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: The workflow for the discovery of novel HDAC3 inhibitors. The number refers to the amount of chemical entities that entered the next component of the workflow.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques:

Eleven cherry-picked and purchased compounds, and their inhibitory activity on HDAC3 in terms of inhibition rate (%) at 10 μM.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: Eleven cherry-picked and purchased compounds, and their inhibitory activity on HDAC3 in terms of inhibition rate (%) at 10 μM.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques: Activity Assay, Inhibition, Positive Control

Inhibitory effects of the hit compound 2 and its derivatives from substructure search on HDAC3.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: Inhibitory effects of the hit compound 2 and its derivatives from substructure search on HDAC3.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques:

The modes of compound 2 (A), 2–1 (B) and 2–2 (C) bound to HDAC3, predicted by FRED. Colour codes: light blue, HDAC3; green, hit compounds; blue sphere, zinc ion.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: The modes of compound 2 (A), 2–1 (B) and 2–2 (C) bound to HDAC3, predicted by FRED. Colour codes: light blue, HDAC3; green, hit compounds; blue sphere, zinc ion.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques:

Activity profiling of three hit compounds, i.e. 2 , 2–1 and 2–2 against a panel of HDAC isoforms.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: Activity profiling of three hit compounds, i.e. 2 , 2–1 and 2–2 against a panel of HDAC isoforms.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques: Activity Assay

Selectivity index (SI) of three HDAC3 inhibitors over other HDAC isoforms.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: Selectivity index (SI) of three HDAC3 inhibitors over other HDAC isoforms.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques: